Operations Director for Cryo-EM Core

Company: Johns Hopkins University
Location: Baltimore
Posted on: November 13, 2024

Job Description:

School: Zanvyl Krieger School of Arts and SciencesDepartment/Program: Department of BiologyThe Johns Hopkins University invites applications for Operations Director of the Cryo-EM Core located on the Homewood Campus. This is a full-time, non-tenure track position supported by the Krieger School of Arts and Sciences. The Cryo-EM Core houses instrumentation serving the diverse research interests of Johns Hopkins University. The current scope of the Homewood cryo-EM facility includes: 1 Titan Krios, 1 Helios Hydra Bio (to be purchased), 1 Talos200, 1 T12, all sample preparation tools such as Vitrobot, and initial data storage/transfer and pre-processing capabilities.The Operations Director of the Cryo-EM shared resource core at Johns Hopkins University (Homewood Campus) is responsible for the scientific and strategic oversight, as well as the implementation of state-of-the-art technologies for cryo-EM imaging, in support of research projects of a broad spectrum of faculty from our institution. The Operations Director will interface closely with their counterpart, the Operations Director of the cryo-EM core at the School of Medicine Campus, to implement a world-class cryo-EM facility across Johns Hopkins campuses, which together will function as an integrated team, sharing expertise and support. The Operations director will maintain a high level of professional expertise and scientific networking within the global cryo-EM community. -Responsibilities: -? Implement and maintain state-of-the-art technologies and expertise on the Homewood campus that will support cryo-EM and cryo-ET data collection. Ensure that all instrumentation and equipment operate efficiently and produce data of the highest possible quality. Maintain appropriate documentation for the shared resource.? Train users to become independent in sample preparation, microscope use, data collection, and initial pre-processing of data. Create and implement educational programs that will serve the needs of the scientific user community and promote the scientific programs of the cryo-EM shared resource.? Attract and retain outstanding research staff to support daily operations as needed.? Supervise staff scientists to ensure the highest standards of microscope operation, data production and collaboration with lab members.? Communicate ongoing progress to user groups and advisory committees and act as a key interface to engage new projects across the Johns Hopkins campuses.? Integrate with the Operations Director and support staff at the cryo-EM facility at the Johns Hopkins School of Medicine to support each-other's technical and operational goals, ensuring that resources are accessible to all users across Hopkins.? Participate in external funding applications, e.g. instrumentation grants, large-scale Center grants and collaborative grant applications, which will be essential for the health of cryo-EM. Provide support for Johns Hopkins investigators in obtaining preliminary data and writing grant applications aimed at obtaining research grants involving cryo-EM applications.? Communicate with vendors about maintenance and upgrade of equipment as well as opportunities offered by new instrumentation, thus ensuring that the shared resource represents the state-of-the-art in cryo-EM.? Work with leadership in the Departments of Biology and Biophysics, and the Krieger School of Arts and Sciences, in developing budgets and meeting financial expectations of the cryo-EM shared resourceQualifications

• Ph.D. qualification coupled with a three-year background in practical cryo-EM applications within a technical or research laboratory setting.Preferred Qualifications:? Doctoral degree in biochemistry, biology, chemistry, physics, or a related field.? Proficiency in utilizing Thermo Fisher Scientific microscopes and grid preparation tools, including Vitrobot, CP3-Plunger, and other associated instruments.? Specialized knowledge in contemporary cryo-EM methodologies, encompassing data collection (EPU, Serial EM, or Leginon) and proficiency in various image processing software packages (Relion, cryoSPARC, EMAN2, cisTEM, Sphire).? Previous involvement in structural biology, particularly in macromolecular model construction using tools such as Chimera and Coot, along with experience in employing structure validation tools.? Exceptional technical acumen, effective communication skills, and a demonstrated ability in teaching.Candidates should include a cover letter describing their principal expertise and accomplishments, a complete resume, and the names and contact information for at least three references (two additional letters may be required at a later date). -The Johns Hopkins University is committed to equal opportunity for its faculty, staff, and students. To that end, the university does not discriminate on the basis of sex, gender, marital status, pregnancy, race, color, ethnicity, national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status or other legally protected characteristic. The university is committed to providing qualified individuals access to all academic and employment programs, benefits and activities on the basis of demonstrated ability, performance and merit without regard to personal factors that are irrelevant to the program involved.Pre-Employment InformationThe successful candidate(s) for this position will be subject to a pre-employment background check.If you are interested in applying for employment with The Johns Hopkins University and require special assistance or accommodation during any part of the pre-employment process, please contact the HR Business Services Office at jhurecruitment@jhu.edu . For TTY users, call via Maryland Relay or dial 711. For more information about workplace accommodations or accessibility at Johns Hopkins University, please visit accessibility.jhu.edu .The following additional provisions may apply depending on which campus you will work. Your recruiter will advise accordingly.The pre-employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those employees who provide results of blood tests or immunization documentation from their own health care providers. Any vaccinations required for these diseases will be given at no cost in our Occupational Health office.In keeping with the mandates of the Jeanne Clery Disclosure of Campus Security Policy and Campus Crime Statistics Act (Clery Act),the University's Annual Report contains statistics of certain crimes that are reported and that occurred on campus, in certainoff-campus buildings or property owned or controlled by the University or an officially recognized student organization, and onpublic property within or immediately adjacent to and accessible from the campus for the three most recent calendar years. Also includedare campus security policies including those related to missing student notifications, alcohol and drug use, sexual assault, relationshipviolence, and stalking, crime prevention, the reporting of crimes, and fire safety policies and statistics. All Johns Hopkins faculty,staff and students are encouraged to read and print out the report at http://security.jhu.edu/_template-assets/documents/annual_report.pdf and to report all criminal incidents promptly to your respective security department.A printed copy of the report may be obtained from the following university security offices or personnel: Homewood (410-516-4631);Peabody Institute (667-208-6608); Medical Institutions (410-614-3473); Applied Physics Laboratory (443-778-4805);Harbor East Campus (410-234-9301); Columbia Center (410-516-9700); SAIS Bologna Center (202-663-5808, Int. +39.051.2917.811);Washington Centers - KSAS (202-663-5808), SAIS (202-663-5808), Carey Business School (202-663-5808);Hopkins-Nanjing Center (202-663-5808, Int. +86.25.8359.2436); Montgomery County Campus (301-294-7011) and Barcelona, Spain (Int. +34.93.542.25.99).
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